Article
A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.
Investigative ophthalmology & visual science - 5 Dec 2012
Meng Weihua, Butterworth Jacqueline, Bradley Declan T, Hughes Anne E, Soler Vincent, Calvas Patrick, Malecaze Francois
Abstract excerpt
PURPOSE: Myopia is a complex trait affected by both genetic and environmental factors. High myopia is associated with increased risk of sight threatening eye disorders such as retinal detachment. The purpose of this genome-wide association study was to identify susceptibility genes contributing to high myopia in the French population. METHODS: High myopic cases were genotyped using Affymetrix SNP 6.0 chips and...
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