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Article

An essential role for the association of CD47 to SHPS-1 in skeletal remodeling.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2011

Maile Laura A, DeMambro Victoria E, Wai Christine, Lotinun Sutada, Aday Ariel W, Capps Byron E, Beamer Wesley G, Rosen Clifford J, Clemmons David R

Abstract excerpt

Integrin-associated protein (IAP/CD47) has been implicated in macrophage-macrophage fusion. To understand the actions of CD47 on skeletal remodeling, we compared Cd47(-/-) mice with Cd47(+/+) controls. Cd47(-/-) mice weighed less and had decreased areal bone mineral density compared with controls. Cd47(-/-) femurs were shorter in length with thinner cortices and exhibited lower trabecular bone volume owing to...

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Source

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Identifiers

PMID: 21638321
DOI: 10.1002/jbmr.441
PMCID: PMC3383326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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