Article
A Single Nucleotide Polymorphism of DNA methyltransferase 3B gene is a risk factor for recurrent spontaneous abortion.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2017
Barišić Anita, Pereza Nina, Hodžić Alenka, Ostojić Saša, Peterlin Borut
Abstract excerpt
PROBLEM: Aberrant DNA methylation has been suggested as a potential cause of recurrent spontaneous abortion (RSA). Considering the growing evidence on the important roles of DNA methylation in gametogenesis and early pregnancy, we investigated the potential association of DNA methyltransferase gene polymorphisms (DNMT1 rs2228611, DNMT3A rs1550117, DNMT3B rs1569686) with RSA in Slovenian reproductive couples....
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