Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in the CYP17 gene and recurrent spontaneous abortions.

Archives of gynecology and obstetrics - 1 Feb 2011

Litridis Iakovos, Kapnoulas Neoptolemos, Natisvili Theona, Agiannitopoulos Konstantinos, Peraki Ourania, Ntostis Panagiotis, Pantos Konstantinos, Lamnissou Klea

Abstract excerpt

PURPOSE: The CYP17 gene encodes the enzyme cytochrome P450c17α, which functions at key steps in the synthesis process of human sex steroid hormones. A T/C polymorphism in the 5' promoter region of the CYP17 gene has been described previously. Serum levels of androgens and estrogens have been shown to be elevated in individuals who carry the C substitution (Α2 allele). We hypothesized that variability in genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Habitual
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Greece

Share to Polymorphism, Restriction Fragment Length

Share to Pregnancy

Share to Promoter Regions, Genetic

Share to Steroid 17-alpha-Hydroxylase

Share to Young Adult

Source

Identifiers

PMID: 20069306
DOI: 10.1007/s00404-009-1348-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in the CYP17 gene and recurrent spontaneous abortions.PMID 20069306Read ↗

A polymorphism in the CYP17 gene relates to the risk of recurrent pregnancy loss.Semantic proximity Read ↗

CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. a HuGE review.Semantic proximity Read ↗

Genetic variation in the HSD3B1 gene and recurrent spontaneous abortions.Semantic proximity Read ↗

Association between G1733A (rs6152) polymorphism in androgen receptor gene and recurrent spontaneous abortions in Mexican population.Semantic proximity Read ↗

Cytochrome P450c17alpha 5'-untranslated region *T/C polymorphism in endometriosis.Semantic proximity Read ↗

StuI polymorphism on the androgen receptor gene is associated with recurrent spontaneous abortion.Semantic proximity Read ↗

Evidence for association of the rs605059 polymorphism of HSD17B1 gene with recurrent spontaneous abortions.Semantic proximity Read ↗

Association of the CYP17 gene polymorphism with risk for uterine leiomyoma in Brazilian women.Semantic proximity Read ↗

Evidence for association of the G1733A polymorphism of the androgen receptor gene with recurrent spontaneous abortions.Semantic proximity Read ↗

Genetic variation of the CYP17 and susceptibility to endometrial cancer: a meta-analysis.Semantic proximity Read ↗

Investigations on the genetic polymorphism in the region of CYP17 gene encoding 5'-UTR in patients with polycystic ovarian syndrome.Semantic proximity Read ↗

CYP17 gene polymorphic sequence variation is associated with hyperandrogenism in Kashmiri women with polycystic ovarian syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.