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Article

TS gene polymorphisms are not good markers of response to 5-FU therapy in stage III colon cancer patients.

Cellular oncology (Dordrecht, Netherlands) - 1 Aug 2011

Fariña-Sarasqueta A, Gosens M J E M, Moerland E, van Lijnschoten I, Lemmens V E P P, Slooter G D, Rutten H J T, van den Brule Adriaan J C

Abstract excerpt

AIM: Although the predictive and prognostic value of thymidylate synthase (TS) expression and gene polymorphism in colon cancer has been widely studied, the results are inconclusive probably because of methodological differences. With this study, we aimed to elucidate the role of TS gene polymorphisms genotyping in therapy response in stage III colon carcinoma patients treated with 5-FU adjuvant chemotherapy....

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Identifiers

PMID: 21630057
DOI: 10.1007/s13402-011-0030-z
PMCID: PMC12994960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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