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Mitochondrial Biogenesis in Health and Disease. Molecular and Therapeutic Approaches

12 Sept 2014

Abstract excerpt

Mitochondrial biogenesis (MB) is the essential mechanism by which cells control the number of mitochondria. Cells respond to different physiologic, metabolic, and pathologic changes by regulating this organelle with high morphological and functional adaptability. A considerable number of proteins, transcription factors, upstream regulatory proteins and secondary mechanisms are involved in MB and the stabilization...

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PMID: 24606801
DOI: 10.2174/1381612820666140306095106

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