Article
The insulin-like growth factor 2 receptor gene Gly1619Arg polymorphism and idiopathic recurrent spontaneous abortion.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Apr 2012
Pereza Nina, Ostojić Saša, Volk Marija, Maver Aleš, Kapović Miljenko, Peterlin Borut
Abstract excerpt
OBJECTIVE: The insulin-like growth factor 2 (IGF2) and its receptor (IGF2R) are important regulators of placental function and fetal growth. Our aim was to investigate the association between IGF2R gene Gly1619Arg G>A polymorphism and recurrent spontaneous abortion (RSA). METHODS: Polymerase chain reaction and restriction fragment length polymorphism methods were performed to identify the genotypes in 149 couples...
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