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Article

High resolution melting analysis to genotype the most common variants in the HFE gene.

Clinical chemistry and laboratory medicine - 1 Sept 2011

Marotta Roberta V, Turri Olivia, Morandi Antonella, Murano Manuela, d'Eril Gianlodovico Melzi, Biondi Maria Luisa

Abstract excerpt

BACKGROUND: High resolution melting (HRM) analysis of PCR amplicons was recently introduced as a closed-tube, rapid, and inexpensive method of genotyping. This study evaluated this system as an option for detecting the three most common mutations in the HFE gene (C282Y, H63D, S65C), accounting for the main form of hereditary haemochromatosis. METHODS: Ninety samples, previously screened by direct sequencing, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21627541
DOI: 10.1515/CCLM.2011.237

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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