Article
Transcriptional regulation of the cytR repressor gene of Escherichia coli: autoregulation and positive control by the cAMP/CAP complex.
Molecular microbiology - 1 Mar 1990
Gerlach P, Valentin-Hansen P, Bremer E
Abstract excerpt
The Escherichia coli cytR-encoded repressor protein (CytR) controls the expression of several genes involved in nucleoside and deoxynucleoside uptake and metabolism. The cytR promoter was identified by determining the transcriptional initiation site of the cytR gene. A chromosomal cytR-lacZ+ operon fusion was isolated and used to study the regulation of cytR. We show that cytR expression is negatively controlled...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Cyclic AMP
- Cyclic AMP Receptor Protein
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation