Article
Combined effect of stacking and solvation on the spontaneous mutation in DNA.
Physical chemistry chemical physics : PCCP - 28 Aug 2011
Cerón-Carrasco José P, Zúñiga José, Requena Alberto, Perpète Eric A, Michaux Catherine, Jacquemin Denis
Abstract excerpt
In DNA, base pairs are involved in two reciprocal interactions: interbase hydrogen bonds and stacking. Furthermore, base pairs also undergo the effects of the external entities present in the biological environment, such as water molecules and cations. In this contribution, the double spontaneous mutation has been studied with hybrid theoretical tools in a DNA-embedded guanine-cytosine model accounting for the...
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