Article
Retrograde transport of the mannosyltransferase Och1p to the early Golgi requires a component of the COG transport complex.
The Journal of biological chemistry - 17 Sept 2004
Bruinsma Paul, Spelbrink Robert G, Nothwehr Steven F
Abstract excerpt
The yeast COG complex has been proposed to function as a vesicle-tethering complex on an early Golgi compartment, but its role is not fully understood. COG complex mutants exhibit a dramatic reduction in Golgi-specific glycosylation and other defects. Here we show that a strain carrying a COG3 te...
Topics
- Adaptor Proteins, Vesicular Transport
- Animals
- Antibodies
- Endosomes
- Glycosylation
- Golgi Apparatus
- Mannosyltransferases
- Membrane Glycoproteins
- Membrane Proteins
- Monomeric Clathrin Assembly Proteins
- Mutation
- Protein Transport
- Qa-SNARE Proteins
- Qc-SNARE Proteins
- Rabbits
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Vacuoles