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Article

Pleiotropic defects caused by loss of the proteasome-interacting factors Rad23 and Rpn10 of Saccharomyces cerevisiae.

Genetics - 1 Sept 1999

Lambertson D, Chen L, Madura K

Abstract excerpt

Rad23 is a member of a novel class of proteins that contain unprocessed ubiquitin-like (UbL) domains. We showed recently that a small fraction of Rad23 can form an interaction with the 26S proteasome. Similarly, a small fraction of Rpn10 is a component of the proteasome. Rpn10 can bind multiubiquitin chains in vitro, but genetic studies have not clarified its role in vivo. We report here that the loss of both...

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Identifiers

PMID: 10471701
DOI: 10.1093/genetics/153.1.69
PMCID: PMC1460738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Pleiotropic defects caused by loss of the proteasome-interacting factors Rad23 and Rpn10 of Saccharomyces cerevisiae.PMID 10471701Read ↗

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Investigating the importance of proteasome-interaction for Rad23 function.Semantic proximity Read ↗

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