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Article

Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation.

Journal of bacteriology - 1 Jun 1990

Hidaka T, Imai S, Hara O, Anzai H, Murakami T, Nagaoka K, Seto H

Abstract excerpt

An enzyme catalyzing the formation of an unusual C-P bond that is involved in the biosynthesis of the antibiotic bialaphos (BA) was isolated from the cell extract of a mutant (NP71) of Streptomyces hygroscopicus SF1293. This enzyme, carboxyphosphonoenolpyruvate (CPEP) phosphonomutase, was first identified as a protein lacking in a mutant (NP213) defective in one of the steps in the pathway to BA. The first 30...

Topics

Anti-Bacterial Agents
Electrophoresis, Polyacrylamide Gel
Mutation
Organophosphorus Compounds
Phosphoenolpyruvate
Phosphotransferases
Phosphotransferases (Phosphomutases)
Streptomyces

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2160937
DOI: 10.1128/jb.172.6.3066-3072.1990
PMCID: PMC209109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2160937-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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