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Article

Prognostic impact of white blood cell count in intermediate risk acute myeloid leukemia: relevance of mutated NPM1 and FLT3-ITD.

Haematologica - 1 Sept 2011

de Jonge Hendrik J M, Valk Peter J M, de Bont Eveline S J M, Schuringa Jan Jacob, Ossenkoppele Gert, Vellenga Edo, Huls Gerwin

Abstract excerpt

BACKGROUND: High white blood cell count at presentation is an unfavorable prognostic factor for treatment outcome in intermediate cytogenetic risk acute myeloid leukemia. Since the impact of white blood cell count on outcome of subgroups defined by the molecular markers NPMc(+) and FLT3-internal tandem duplication (ITD) is unknown, we addressed this issue. DESIGN AND METHODS: We studied the effect of white blood...

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Identifiers

PMID: 21606167
DOI: 10.3324/haematol.2011.040592
PMCID: PMC3166101

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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