Article
Influence of FLT3-internal tandem duplication allele burden and white blood cell count on the outcome in patients with intermediate-risk karyotype acute myeloid leukemia.
Cancer - 15 Dec 2012
How Jonathan, Sykes Jenna, Gupta Vikas, Yee Karen W L, Schimmer Aaron D, Schuh Andre C, Minden Mark D, Kamel-Reid Suzanne, Brandwein Joseph M
Abstract excerpt
BACKGROUND: In patients with acute myeloid leukemia (AML), testing for fms-like tyrosine kinase-3 (FLT3)-internal tandem duplication (FLT3-ITD) and nucleophosmin-1 (NPM1) mutations can allow for further prognostic subclassification, but less is known about the effects of FLT3-ITD allele burden an...
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