Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Analysis of drug-resistant multi-loci mutation of P area of HBV genome in 32 patients with chronic hepatitis B].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Jun 2011

Ye Fei, Li Xiao-Ou, Guo Jian-Chun, Wu Jing

Abstract excerpt

OBJECTIVE: In order to deeply understand the effects of nucleoside analogues to HBV DNA polymerase area, which initiate a state of drug resistance due to HBV genome mutation. METHODS: Using PCR product direct sequencing method to test the gene sequence of P area of HBV genome of the patients who taking nucleoside analogues and showing signs of virologic breakthrough. RESULTS: More resistance mutations can be find...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Viral
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 21977594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Analysis of drug-resistant multi-loci mutation of P area of HBV genome in 32 patients with chronic hepatitis B].PMID 21977594Read ↗

[Clinical significance of drug resistance-associated mutations in treatment of hepatitis C with direct-acting antiviral agents].Semantic proximity Read ↗

[The drug resistance mutation detection and relevant factors analysis of HBV P region in chronic hepatitis B patients in Weifang City, Shandong Province].Semantic proximity Read ↗

[Mutation patterns in the RT region of hepatitis B virus P gene in patients treated with nucleoside/nucleotide analogs].Semantic proximity Read ↗

[Analysis of risk factors for drug resistant mutations in the reverse transcriptase region in chronic hepatitis B virus-infected patients].Semantic proximity Read ↗

[Analysis of characteristics of drug resistance gene mutation in HBV RT region of hepatitis B infected patients].Semantic proximity Read ↗

[Drug-resistant mutations in hepatitis B virus found in chronic HBV carriers using PCR sequencing technology].Semantic proximity Read ↗

Evolution of drug-resistant mutations in HBV genomes in patients with treatment failure during the past seven years (2010-2016).Semantic proximity Read ↗

Drug Resistance Mutations in the Polymerase Gene of Hepatitis B Virus in Three Generations of Patients with Chronic Hepatitis BSemantic proximity Read ↗

[Mutation incidence of and resistant sites in HBV after long-term nucleoside analogs therapy].Semantic proximity Read ↗

Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations.Semantic proximity Read ↗

[Multiple-site analysis of HBV drug-resistant mutations in 340 patients with chronic hepatitis B].Semantic proximity Read ↗

[Mechanisms of drug resistance in hepatitis viruses B and C].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.