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Article

Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2011

Guimarães José Luiz Miranda, Ayrizono Maria de Lurdes, Coy Cláudio Saddy Rodrigues, Lima Carmen Silvia Passos

Abstract excerpt

This pilot study has compared the polymorphic genotype frequencies of methylenetetrahydrofolate reductase (MTHFR A1298C and C677T), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G), and thymidylate synthase (TS 2R/3R) in 113 patients with sporadic colorectal adenocarcinoma (SCA) and 188 healthy blood donors, used as matched controls. The aim was to assess the role of these genotypes in...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21603981
DOI: 10.1007/s13277-011-0185-2

Genes

MTHFR
MTR
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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