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Article

Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris.

Journal of dermatological science - 1 Jul 2011

Hata Tsuyoshi, Nishifuji Koji, Shimoda Kouji, Sasaki Takashi, Yamada Taketo, Nishikawa Takeji, Koyasu Shigeo, Amagai Masayuki

Abstract excerpt

BACKGROUND: An active disease mouse model of pemphigus vulgaris (PV) was developed using the adoptive transfer of splenocytes from Dsg3(-/-) mice with a mixed C57BL/6J (B6) and 129/Sv genetic background into B6-Rag2(-/-) mice. Further immunological investigation is needed to resolve the genetic m...

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Source

Identifiers

PMID: 21602032
DOI: 10.1016/j.jdermsci.2011.04.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21602032-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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