Article
Confirmation of a disease model of pemphigus vulgaris: characterization and correlation between disease parameters in 90 mice.
Experimental dermatology - 1 Aug 2010
Holm Thomas Lindebo, Markholst Helle
Abstract excerpt
Pemphigus vulgaris (PV) is a chronic autoimmune bullous disease associated with immunoglobulin G (IgG) autoantibodies against desmoglein 3 (Dsg3). Previously, a mouse model of PV was established by adoptive transfer of naive splenocytes from Dsg3(-/-) mice to Rag2(-/-) mice. The model is unique a...
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