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Article

Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris.

The Journal of investigative dermatology - 1 Jan 2002

Ohyama Manabu, Amagai Masayuki, Tsunoda Kazuyuki, Ota Takayuki, Koyasu Shigeo, Hata Jun-ichi, Umezawa Akihiro, Nishikawa Takeji

Abstract excerpt

Pemphigus vulgaris is an autoimmune blistering disease of the skin and mucous membranes that is caused by anti-desmoglein 3 IgG autoantibodies. Recently, we generated an active disease mouse model for pemphigus vulgaris by adoptive transfer of splenocytes from immunized desmoglein 3-/- mice to Rag2-/- mice. In this study, we performed immunologic and histopathologic studies using this pemphigus vulgaris model in...

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Identifiers

PMID: 11851895
DOI: 10.1046/j.0022-202x.2001.01643.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Immunologic and histopathologic characterization of an active disease mouse model for pemphigus vulgaris.PMID 11851895Read ↗

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