Article
A polymorphism in IL28B distinguishes exposed, uninfected individuals from spontaneous resolvers of HCV infection.
Gastroenterology - 1 Jul 2011
Knapp Susanne, Warshow Usama, Ho K M Alexander, Hegazy Doha, Little Ann-Margaret, Fowell Andrew, Alexander Graeme, Thursz Mark, Cramp Matthew, Khakoo Salim I
Abstract excerpt
BACKGROUND & AIMS: Polymorphisms in the interleukin-28B (IL28B) gene are associated with outcomes from infection with hepatitis C virus (HCV). However, the role of these polymorphisms in protecting injection drug users who are at high risk for HCV infection but do not have detectable antibodies against HCV or HCV RNA (exposed uninfected) has not been demonstrated. We investigated whether these individuals have...
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