Article
Influence of N-linked glycans on intracellular transport of hepatitis C virus E1 chimeric glycoprotein and its role in pseudotype virus infectivity.
Virology - 1 Jul 2004
Beyene Aster, Basu Arnab, Meyer Keith, Ray Ranjit
Abstract excerpt
We have previously reported a functional role associated with hepatitis C virus (HCV) E1 glycoprotein using vesicular stomatitis virus (VSV)/HCV pseudotype. In this study, we have investigated the role of glycosylation upon intracellular transport of chimeric E1-G, and in infectivity of the pseudotyped virus. Interestingly, surface expressed E1-G exhibited sensitivity to Endoglycosidase H (Endo H) treatment,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
