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Article

Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.

Cell stem cell - 3 Jun 2011

Liu Guang-Hui, Suzuki Keiichiro, Qu Jing, Sancho-Martinez Ignacio, Yi Fei, Li Mo, Kumar Sachin, Nivet Emmanuel, Kim Jessica, Soligalla Rupa Devi, Dubova Ilir, Goebl April, Plongthongkum Nongluk, Fung Ho-Lim, Zhang Kun, Loring Jeanne F, Laurent Louise C, Izpisua Belmonte Juan Carlos

Abstract excerpt

Combination of stem cell-based approaches with gene-editing technologies represents an attractive strategy for studying human disease and developing therapies. However, gene-editing methodologies described to date for human cells suffer from technical limitations including limited target gene siz...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21596650
DOI: 10.1016/j.stem.2011.04.019
PMCID: PMC3480729

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-21596650-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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