Advances in Gene Therapy Techniques to Treat LRRK2 Gene Mutation.

Abstract excerpt

Leucine-rich repeat kinase 2 (LRRK2) gene mutation is an autosomal dominant mutation associated with Parkinson's disease (PD). Among LRRK2 gene mutations, the LRRK2 G2019S mutation is frequently involved in PD onset. Currently, diverse gene correction tools such as zinc finger nucleases (ZFNs), helper-dependent adenoviral vector (HDAdV), the bacterial artificial chromosome-based homologous recombination...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Editing
• Share to Genetic Therapy
• Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2