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Article

The Epstein-Barr virus (EBV) ORI1yt enhancer is not B-cell specific and does not respond synergistically to the EBV transcription factors R and Z.

Journal of virology - 1 Jun 1990

Gruffat H, Moreno N, Sergeant A

Abstract excerpt

The Epstein-Barr virus DR promoter is located upstream of the PstI repeats, and in addition to the TATA box, it contains an upstream region (positions -69 to -220) responsive to EB1 (Z) (the BZLF1-encoded transcription factor) and an enhancer with two functionally distinct domains, A and B. Domain B has been described as a B-cell-specific EB1-responsive element (P. M. Lieberman, J. M. Hardwick, and S. D. Hayward,...

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Identifiers

PMID: 2159545
DOI: 10.1128/JVI.64.6.2810-2818.1990
PMCID: PMC249462

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The Epstein-Barr virus (EBV) ORI1yt enhancer is not B-cell specific and does not respond synergistically to the EBV transcription factors R and Z.PMID 2159545Read ↗

The enhancer factor R of Epstein-Barr virus (EBV) Is a sequence-specific DNA binding proteinSemantic proximity Read ↗

An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators.Semantic proximity Read ↗

Transcriptional interference between the EBV transcription factors EB1 and R: both DNA-binding and activation domains of EB1 are required.Semantic proximity Read ↗

Marked Variation in Response of Consensus Binding Elements for the Rta Protein of Epstein-Barr VirusSemantic proximity Read ↗

Activation of the Epstein-Barr virus DNA polymerase promoter by the BRLF1 immediate-early protein is mediated through USF and E2F.Semantic proximity Read ↗

The Epstein-Barr virus BRLF1 immediate-early gene product transactivates the human immunodeficiency virus type 1 long terminal repeat by a mechanism which is enhancer independent.Semantic proximity Read ↗

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Viral and cellular factors influence the activity of the Epstein-Barr virus BCR2 and BWR1 promoters in cells of different phenotype.Semantic proximity Read ↗

Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta.Semantic proximity Read ↗

EBNA-2 transactivates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virusSemantic proximity Read ↗

Rescue of the Epstein-Barr virus BZLF1 mutant, Z(S186A), early gene activation defect by the BRLF1 gene product.Semantic proximity Read ↗

Identification of the 12-O-tetradecanoylphorbol-13-acetate-responsive enhancer of the MS gene of the Epstein-Barr virus.Semantic proximity Read ↗

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