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Article

The enhancer factor R of Epstein-Barr virus (EBV) Is a sequence-specific DNA binding protein

1 Jan 1990

Abstract excerpt

In cells latently infected with EBV, the switch from latency to productive infection is linked to the expression of two EBV transcription factors called EB1 (or Z) and R. EB1 is an upstream element factor which has partial homology to the AP1/ATF family, whereas R is an enhancer factor. In the R-responsive enhancer of the replication origin only active during the EBV lytic cycle (ORIIyt), R-responsive elements...

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Identifiers

PMID: 2175879
DOI: 10.1093/nar/18.23.6835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The enhancer factor R of Epstein-Barr virus (EBV) Is a sequence-specific DNA binding proteinPMID 2175879Read ↗

Transcriptional interference between the EBV transcription factors EB1 and R: both DNA-binding and activation domains of EB1 are required.Semantic proximity Read ↗

The Epstein-Barr virus (EBV) ORI1yt enhancer is not B-cell specific and does not respond synergistically to the EBV transcription factors R and Z.Semantic proximity Read ↗

Epstein-Barr virus transcription activator R upregulates BARF1 expression by direct binding to its promoter, independent of methylation.Semantic proximity Read ↗

An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators.Semantic proximity Read ↗

Characterization of the DNA-binding site repertoire for the Epstein - Barr virus transcription factor RSemantic proximity Read ↗

Marked Variation in Response of Consensus Binding Elements for the Rta Protein of Epstein-Barr VirusSemantic proximity Read ↗

An EBNA-1-dependent enhancer acts from a distance of 10 kilobase pairs to increase expression of the Epstein-Barr virus LMP geneSemantic proximity Read ↗

Activation of the Epstein-Barr virus DNA polymerase promoter by the BRLF1 immediate-early protein is mediated through USF and E2F.Semantic proximity Read ↗

EBNA-2 transactivates a lymphoid-specific enhancer in the BamHI C promoter of Epstein-Barr virusSemantic proximity Read ↗

Cellular transcription factors recruit viral replication proteins to activate the Epstein–Barr virus origin of lytic DNA replication, oriLytSemantic proximity Read ↗

EBNA1 can link the enhancer element to the initiator element of the Epstein-Barr virus plasmid origin of DNA replicationSemantic proximity Read ↗

A transcription factor with homology to the AP‐1 family links RNA transcription and DNA replication in the lytic cycle of Epstein‐Barr virus.Semantic proximity Read ↗

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