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Article

An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators.

Journal of virology - 1 Jan 1990

Cox M A, Leahy J, Hardwick J M

Abstract excerpt

The EA-R and NotI repeat genes of Epstein-Barr virus (EBV) are oriented head to head and separated by a 1,000-base-pair (bp) divergent promoter region. We have identified functional domains within this divergent promoter which are important for regulation of the rightward EA-R gene. Both the R transactivator (Rta) and the Z transactivator (Zta) increase the abundance of correctly initiated EA-R transcripts. A...

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Identifiers

PMID: 2152819
DOI: 10.1128/JVI.64.1.313-321.1990
PMCID: PMC249104

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators.PMID 2152819Read ↗

The enhancer factor R of Epstein-Barr virus (EBV) Is a sequence-specific DNA binding proteinSemantic proximity Read ↗

Marked Variation in Response of Consensus Binding Elements for the Rta Protein of Epstein-Barr VirusSemantic proximity Read ↗

The Epstein-Barr virus (EBV) ORI1yt enhancer is not B-cell specific and does not respond synergistically to the EBV transcription factors R and Z.Semantic proximity Read ↗

Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta.Semantic proximity Read ↗

Induction of the Early Growth Response 1 Gene by Epstein-Barr Virus Lytic Transactivator ZtaSemantic proximity Read ↗

Transcriptional interference between the EBV transcription factors EB1 and R: both DNA-binding and activation domains of EB1 are required.Semantic proximity Read ↗

B-cell lines immortalized with an Epstein-Barr virus mutant lacking the Cp EBNA2 enhancer are biased toward utilization of the oriP-proximal EBNA gene promoter Wp1.Semantic proximity Read ↗

Activation of the Epstein-Barr virus DNA polymerase promoter by the BRLF1 immediate-early protein is mediated through USF and E2F.Semantic proximity Read ↗

Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.Semantic proximity Read ↗

The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2.Semantic proximity Read ↗

The Epstein-Barr virus (EBV) DNA polymerase accessory protein, BMRF1, activates the essential downstream component of the EBV oriLyt.Semantic proximity Read ↗

Essential Role of Rta in Lytic DNA Replication of Epstein-Barr VirusSemantic proximity Read ↗

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