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Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies.

Medicine - 1 Oct 2016

Zhuo Xianlu, Song Jue, Liao Jian, Zhou Wei, Ye Huiping, Li Qi, Xiang Zhaolan, Zhang Xueyuan

Abstract excerpt

BACKGROUND: Previous reports showed that CYP2E1 RsaI/PstI polymorphism may be a risk factor for cancers. Published meta-analyses in 2010 and 2011, respectively, on the relationship of CYP2E1 RsaI/PstI polymorphisms with the susceptibility to head and neck carcinoma (HNC) have generated inconsistent results. Thus, this study aimed to conduct an updated meta-analysis involving published studies up to Nov 2015 to...

Topics

Carcinoma, Squamous Cell
Cytochrome P-450 CYP2E1
DNA, Neoplasm
Genetic Predisposition to Disease
Genotype
Head and Neck Neoplasms
Humans
Polymorphism, Genetic
Squamous Cell Carcinoma of Head and Neck

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27787372
DOI: 10.1097/MD.0000000000005156
PMCID: PMC5089101

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