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The role of human single-stranded DNA binding protein and its individual subunits in simian virus 40 DNA replication.

1 May 1990

Abstract excerpt

Human single-stranded DNA binding protein (human SSB) is a multisubunit protein containing polypeptides of 70, 34, and 11 kDa that is required for SV40 DNA replication in vitro. In this report we identify the functions of the SSB and its individual subunits in SV40 DNA replication. The 70 kDa subunit was found to bind to single-stranded DNA, whereas the other subunits did not. Four monoclonal antibodies against...

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PMID: 2159011
DOI: 10.1016/s0021-9258(19)39170-7

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