Article
Analysis of lethal mutations induced in a mutator strain that activates transposable elements in Caenorhabditis elegans.
Genome - 1 Feb 1990
Clark D V, Johnsen R C, McKim K S, Baillie D L
Abstract excerpt
A screen was conducted for lethal mutations in the nematode Caenorhabditis elegans in a strain containing the mutator mut-4 (st700)I to examine the nature of mutator-induced lethal mutations within two large chromosomal regions comprising a total of 49 map units (linkage group IV (right) and linkage group V (left)). The genetic analysis of 28 lethal mutations has revealed that the mutator locus mut-4(st700)I...
Topics
- Animals
- Caenorhabditis
- Chromosome Mapping
- Crosses, Genetic
- DNA Transposable Elements
- Female
- Genes, Lethal
- Genes, Recessive
- Genetic Complementation Test
- Genetic Linkage
- Male
