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Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability.

DNA repair - 7 Feb 2011

Arczewska Katarzyna D, Baumeier Christian, Kassahun Henok, Sengupta Tanima, Bjørås Magnar, Kuśmierek Jarosław T, Nilsen Hilde

Abstract excerpt

MutT enzymes prevent DNA damage by hydrolysis of 8-oxodGTP, an oxidized substrate for DNA synthesis and antimutagenic, anticarcinogenic, and antineurodegenerative functions of MutT enzymes are well established. MutT has been found in almost all kingdoms of life, including many bacterial species, yeasts, plants and mammals. However, a Caenorhabditis elegans MutT homologue was not previously identified. Here, we...

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PMID: 21111690
DOI: 10.1016/j.dnarep.2010.10.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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