Article

High frequency of Exon 20 S768I <i>EGFR</i> mutation detected in malignant pleural effusions: a poor prognosticator of NSCLC?

2019-12-14

Abstract excerpt

Lung cancer is the cause of a fourth of all cancer-related deaths. About a third of all lung adenocarcinoma tumours harbour mutations on exons 18, 19, 20 and 21 of the epidermal growth factor receptor ( EGFR ) gene. Detection of these mutations allows for targeted therapies in the form of EGFR Tyrosine kinase inhibitors. In our study, we utilized malignant pleural effusions (MPEs) as “liquid biopsies” to detect EG...

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Literature Corpus work: c3192786-0a9b-50d0-afd5-df685fc97545
DOI: 10.1101/2019.12.08.19014167

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