GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt.

doi:10.1158/1055-9965.EPI-10-1306

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Article

GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2011

Goerlitz David, El Daly Mai, Abdel-Hamid Mohamed, Saleh Doa'a A, Goldman Lenka, El Kafrawy Sherif, Hifnawy Tamer, Ezzat Sameera, Abdel-Aziz Mohamed A, Zaghloul Mohamed Saad, Ali Saber Rafat, Khaled Hussein, Amr Sania, Zheng Yun-Ling, Mikhail Nabiel, Loffredo Christopher

Abstract excerpt

BACKGROUND: Bladder cancer is the most common male malignancy in Egypt, consists predominantly of urothelial cell carcinoma (UCC) and squamous cell carcinoma (SCC), and disparities in incidence exist between men and women regardless of geographic region. Tobacco smoke exposure and Schistosoma haematobium (SH) infection and the presence of GSTM1, GSTT1, and GPX1 genotypes, as modulators of the carcinogenic effect...

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Identifiers

PMID: 21586620
DOI: 10.1158/1055-9965.EPI-10-1306
PMCID: PMC3136366

Genes

GPX1
GSTM1
GSTT1
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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