Article
Induction of SOS genes in Escherichia coli and mutagenesis in Salmonella typhimurium by fluoroquinolones.
Mutagenesis - 1 Jan 1990
Ysern P, Clerch B, Castańo M, Gibert I, Barbé J, Llagostera M
Abstract excerpt
The induction of several SOS genes of Escherichia coli by fluoroquinolones has been studied. Three different SOS gene fusions (recA::lacZ, umuC::lacZ and sulA::lacZ) have been introduced into the E.coli MC1061 strain to study the induction of these SOS genes in the same genetic background. Data on the basal level of expression of these fusions, as well as their induction by mitomycin C and...
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