Article
The SOS-function-inducing activity of chemical mutagens in Escherichia coli.
Mutation research - 1 Jan 2000
Ohta T, Nakamura N, Moriya M, Shirasu Y, Kada T
Abstract excerpt
The SOS-function-inducing activities of 42 chemical mutagens were investigated in Escherichia coli K12. The induction of the SOS function was assayed by monitoring the beta-galactosidase activity in the sulA::lacZ fusion strain PQ37 . To correct for the inhibitory effects of test chemicals on mRNA or protein synthesis, the level of the constitutive alkaline phosphatase was assayed in parallel. Most of the...
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