The SOS-function-inducing activity of chemical mutagens in Escherichia coli.

doi:10.1016/0167-8817(84)90048-8

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Article

The SOS-function-inducing activity of chemical mutagens in Escherichia coli.

Mutation research - 1 Jan 2000

Ohta T, Nakamura N, Moriya M, Shirasu Y, Kada T

Abstract excerpt

The SOS-function-inducing activities of 42 chemical mutagens were investigated in Escherichia coli K12. The induction of the SOS function was assayed by monitoring the beta-galactosidase activity in the sulA::lacZ fusion strain PQ37 . To correct for the inhibitory effects of test chemicals on mRN...

Topics

Alkaline Phosphatase
Bleomycin
DNA Repair
Enzyme Induction
Escherichia coli
Mutagens
Mutation
RNA, Messenger
beta-Galactosidase

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