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Article

A SINE insertion provides information on the divergence of the HLA-DQA1 and HLA-DQA2 genes.

Immunogenetics - 1 Jan 1990

Del Pozzo G, Guardiola J

Abstract excerpt

The class II region of the human major histocompatibility complex (MHC) contains a cluster of highly polymorphic genes organized into at least three subloci (DR, DQ, and DP), each encoding a subset of surface antigens participating in the modulation of the immune response. Genetic diversity in this system is brought about by two major mechanisms, hypermutation and trans-species evolution. The DQ subregion...

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Identifiers

PMID: 2158485
DOI: 10.1007/BF00204892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A SINE insertion provides information on the divergence of the HLA-DQA1 and HLA-DQA2 genes.PMID 2158485Read ↗

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Recent origin of HLA-DRB1 alleles and implications for human evolution.Semantic proximity Read ↗

An ancient interlocus recombination increases class II MHC DQA diversity in sheep and other Bovidae.Semantic proximity Read ↗

Duplication and polymorphism in the MHC: Alu generated diversity and polymorphism within the PERB11 gene family.Semantic proximity Read ↗

Rhesus macaque class I duplicon structures, organization, and evolution within the alpha block of the major histocompatibility complex.Semantic proximity Read ↗

Segmental exchange between MHC class I genes in a higher primate: recombination in the gorilla between the ancestor of a human non-functional gene and an A locus gene.Semantic proximity Read ↗

Analysis of intron sequences at the class II HLA-DRB1 locus: implications for the age of allelic diversity.Semantic proximity Read ↗

Evidence that most human Alu sequences were inserted in a process that ceased about 30 million years ago.Semantic proximity Read ↗

Allelic diversification at the class II DQB locus of the mammalian major histocompatibility complex.Semantic proximity Read ↗

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