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Rhesus macaque class I duplicon structures, organization, and evolution within the alpha block of the major histocompatibility complex.

Molecular biology and evolution - 1 Nov 2004

Kulski Jerzy K, Anzai Tatsuya, Shiina Takashi, Inoko Hidetoshi

Abstract excerpt

The alpha block of the human and chimpanzee major histocompatibility complex (MHC) class I genomic region contains 10 to 11 duplicated MHC class I genes, including the HLA/Patr-A, -G, and -F genes. In comparison, the alpha block of the rhesus macaque (Macaca mulatta, Mamu) has an additional 20 MHC class I genes within this orthologous region. The present study describes the identification and analysis of the...

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PMID: 15269276
DOI: 10.1093/molbev/msh216

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