Article
Regulation of protein kinase A activity by p90 ribosomal S6 kinase 1.
The Journal of biological chemistry - 27 Nov 2009
Gao Xianlong, Patel Tarun B
Abstract excerpt
Previously, we reported that the catalytic subunit of cAMP-dependent protein kinase (PKAc) binds to the active p90 ribosomal S6 kinase 1 (RSK1) (Chaturvedi, D., Poppleton, H. M., Stringfield, T., Barbier, A., and Patel, T. B. (2006) Mol. Cell. Biol. 26, 4586-4600). Herein, by overexpressing hemagglutinin-tagged RSK1 fragments in HeLa cells we have identified the region of RSK1 that is responsible for the...
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