Article
Heterogeneity of immunoglobulin gene rearrangements in B-cell lymphomas.
International journal of cancer - 15 Apr 1990
Kneba M, Bergholz M, Bolz I, Hulpke M, Bätge R, Schauer A, Krieger G
Abstract excerpt
We have examined 69 B-cell non-Hodgkin's lymphomas (NHL) for rearrangements of the immunoglobulin (Ig) or T-cell antigen receptor (TCR) genes. The lymphomas were assigned to the categories of the Kiel classification and their B-cell nature was confirmed by immunostaining. Only 2 cases (with CLL) displayed clonal T beta-chain TCR gene rearrangements together with rearranged heavy- and light-chain Ig genes. The...
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