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Article

Clinical characteristics of high-grade lymphomas with immune genes in germline configuration.

Cancer - 1 Feb 1991

Kneba M, Bolz I, Bergholz M, Bätge R, Nauck M, Nitsche R, Krieger G

Abstract excerpt

In a prospective study of 42 high-grade lymphomas which were categorized according to the Kiel classification, the clinical significance of immune genotyping was studied. Immunoglobulin (Ig) and T-cell receptor (TCR) gene rearrangements were investigated. In 33 cases the immune genotype confirmed the phenotype. In one case with equivocal phenotype a TCR beta-chain rearrangement proved the T-cell origin of the...

Topics

Adolescent
Adult
Child
DNA, Neoplasm
Female
Gene Rearrangement
Genes, Immunoglobulin
Genotype
Humans
Lung Neoplasms
Lymph Nodes
Lymphoma, Non-Hodgkin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Phenotype

Prospective Studies

Source

Identifiers

PMID: 1985755
DOI: 10.1002/1097-0142(19910201)67:3<603::aid-cncr2820670314>3.0.co;2-p

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1985755-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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