Article
Clinical characteristics of high-grade lymphomas with immune genes in germline configuration.
Cancer - 1 Feb 1991
Kneba M, Bolz I, Bergholz M, Bätge R, Nauck M, Nitsche R, Krieger G
Abstract excerpt
In a prospective study of 42 high-grade lymphomas which were categorized according to the Kiel classification, the clinical significance of immune genotyping was studied. Immunoglobulin (Ig) and T-cell receptor (TCR) gene rearrangements were investigated. In 33 cases the immune genotype confirmed the phenotype. In one case with equivocal phenotype a TCR beta-chain rearrangement proved the T-cell origin of the...
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