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Article

Analysis of beta, gamma, and delta T-cell receptor genes in lymphomatoid papulosis: cellular basis of two distinct histologic subsets.

The Journal of investigative dermatology - 1 May 1991

Whittaker S, Smith N, Jones R R, Luzzatto L

Abstract excerpt

To investigate the histogenesis of lymphomatoid papulosis (LYP), we have analyzed the configuration of the beta, gamma, and delta T-cell receptor (TCR) and Ig genes in DNA from 31 biopsies of 18 patients with this condition and also from peripheral blood mononuclear cells of eight of these patients. Immunoglobulin genes were in a germ-line configuration in all patients, and TCR genes were in a germ-line...

Topics

Adult
Aged
Antigens, Differentiation
Antigens, Neoplasm
Female
Gene Rearrangement
Genes, Immunoglobulin
Genotype
Humans
Ki-1 Antigen
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Receptors, Antigen, T-Cell

Receptors, Antigen, T-Cell, alpha-beta

Receptors, Antigen, T-Cell, gamma-delta

Skin Diseases

Source

Identifiers

PMID: 1850775
DOI: 10.1111/1523-1747.ep12471773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1850775-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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