Association of polymorphisms of the serotonergic pathways with clinical traits of impulsive-aggression and suicidality in adolescents: a multi-center study.

doi:10.3109/15622975.2010.518628

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Article

Association of polymorphisms of the serotonergic pathways with clinical traits of impulsive-aggression and suicidality in adolescents: a multi-center study.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Feb 2011

Zalsman Gil, Patya Miriam, Frisch Amos, Ofek Hadas, Schapir Lior, Blum Ilana, Harell Daniella, Apter Alan, Weizman Abraham, Tyano Samuel

Abstract excerpt

OBJECTIVES: Suicidal behaviour runs in families. This study evaluated association between common polymorphisms in the serotonergic and adrenergic candidate genes (HTR2A, 5HTTLPR, and MAOA) and suicidality, psychopathology and aggression in adolescents. METHODS: Four groups of adolescents were included: Suicidal (N=35) and non-suicidal (N=30) psychiatric inpatients, suicide attempters admitted to three psychiatric...

Topics

Adolescent
Adolescent Behavior
Adult
Aggression
Female
Genetic Predisposition to Disease
Humans
Impulsive Behavior
Israel
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Monoamine Oxidase

Polymorphism, Genetic

Receptors, Serotonin, 5-HT2

Serotonin Plasma Membrane Transport Proteins

Suicide, Attempted

Young Adult

Source

Open in PubMed

Identifiers

PMID: 20873971
DOI: 10.3109/15622975.2010.518628

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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