Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

Behavioral and brain functions : BBF - 28 Jun 2011

Murphy Therese M, Ryan Maria, Foster Tom, Kelly Chris, McClelland Roy, O'Grady John, Corcoran Eleanor, Brady John, Reilly Michael, Jeffers Anne, Brown Katherine, Maher Anne, Bannan Noreen, Casement Alison, Lynch Dermot, Bolger Sharon, Tewari Prerna, Buckley Avril, Quinlivan Leah, Daly Leslie, Kelleher Cecily, Malone Kevin M

Abstract excerpt

BACKGROUND: Suicidal behaviour is known to aggregate in families. Patients with psychiatric disorders are at higher risk for suicide attempts (SA), however protective and risk genetic variants for suicide appear to be independent of underlying psychiatric disorders. Here we investigate genetic variants in genes important for neurobiological pathways linked to suicidal behaviour and/or associated endophenotypes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endophenotypes
Share to Excitatory Amino Acid Transporter 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Excitatory Amino Acid Transporter 2

Share to Mental Disorders

Share to Neurotransmitter Agents

Share to Receptor, Serotonin, 5-HT1B

Share to Receptor, trkB

Share to Suicide, Attempted

Source

Open in PubMed Open full text

Identifiers

PMID: 21711518
DOI: 10.1186/1744-9081-7-22
PMCID: PMC3141406

Genes

NTRK2
ABCG1
BDNF
CNR1
COMT
CRHR1
DBH
GABRA5
GABRB2
GABRG2
TPH1
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.PMID 21711518Read ↗

Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future DirectionsSemantic proximity Read ↗

Serotonergic genes and suicide: a systematic review.Semantic proximity Read ↗

SLC6A3 (DAT1) as a novel candidate biomarker gene for suicidal behavior: a pilot studySemantic proximity Read ↗

Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factorsSemantic proximity Read ↗

The Impact of COMT and Childhood Maltreatment on Suicidal Behaviour in Affective Disorders.Semantic proximity Read ↗

A Study of Candidate Genes Associated with Suicide Attempts in the Kazakh Population in Astana, Kazakhstan.Semantic proximity Read ↗

Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders.Semantic proximity Read ↗

Association of the 5HTR2A gene with suicidal behavior: case-control study and updated meta-analysis.Semantic proximity Read ↗

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.Semantic proximity Read ↗

Role of serotonergic-related systems in suicidal behavior: Data from a case-control association study.Semantic proximity Read ↗

Association of NTRK2 gene with suicidality: a meta-analysis.Semantic proximity Read ↗

Family-based study of HTR2A in suicide attempts: observed gene, gene × environment and parent-of-origin associations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.