Article
Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
International journal of hematology - 1 Jun 2011
Tanabe Tsuyoshi, Yamaguchi Natsu, Matsuda Koichi, Yamazaki Keiko, Takahashi Satoshi, Tojo Arinobu, Onizuka Makoto, Eishi Yoshinobu, Akiyama Hideki, Ishikawa Jun, Mori Takehiko, Hara Masamichi, Koike Kazutoshi, Kawa Keisei, Kawase Takakazu, Morishima Yasuo, Amano Hiroki, Kobayashi-Miura Mikiko, Kakamu Takeyasu, Nakamura Yusuke, Asano Shigetaka, Fujita Yasuyuki
Abstract excerpt
Members of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family participate in the innate immune system, exerting widespread effects on cytokine secretion, autophagy, and apoptosis. Recent studies in Caucasians revealed the association between mutants of NOD2, a member o...
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