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Article

Clustering heart rate dynamics is associated with β-adrenergic receptor polymorphisms: analysis by information-based similarity index.

PloS one - 4 May 2011

Yang Albert C, Tsai Shih-Jen, Hong Chen-Jee, Wang Cynthia, Chen Tai-Jui, Liou Ying-Jay, Peng Chung-Kang

Abstract excerpt

BACKGROUND: Genetic polymorphisms in the gene encoding the β-adrenergic receptors (β-AR) have a pivotal role in the functions of the autonomic nervous system. Using heart rate variability (HRV) as an indicator of autonomic function, we present a bottom-up genotype-phenotype analysis to investigate the association between β-AR gene polymorphisms and heart rate dynamics. METHODS: A total of 221 healthy Han Chinese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Share to Receptors, Adrenergic, beta-1

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Identifiers

PMID: 21573230
DOI: 10.1371/journal.pone.0019232
PMCID: PMC3087751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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