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Article

Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise.

Physiological genomics - 1 Sept 2015

Kohli Utkarsh, Diedrich André, Kannankeril Prince J, Muszkat Mordechai, Sofowora Gbenga G, Hahn Maureen K, English Brett A, Blakely Randy D, Stein C Michael, Kurnik Daniel

Abstract excerpt

Heart rate recovery (HRR) after exercise is an independent predictor of adverse cardiovascular outcomes. HRR is mediated by both parasympathetic reactivation and sympathetic withdrawal and is highly heritable. We examined whether common genetic variants in adrenergic and cholinergic receptors and transporters affect HRR. In our study 126 healthy subjects (66 Caucasians, 56 African Americans) performed an 8 min...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to ADRB1 gene

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Adrenergic, alpha-2

Share to Receptors, Adrenergic, beta-1

Source

Open in PubMed Open full text

Identifiers

PMID: 26058836
DOI: 10.1152/physiolgenomics.00124.2014
PMCID: PMC4556937

Genes

ADRB1
ADRB2
GRK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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