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Article

Relationship between human evolution and neurally mediated syncope disclosed by the polymorphic sites of the adrenergic receptor gene α2B-AR.

PloS one - 1 Jan 2015

Komiyama Tomoyoshi, Hirokawa Takatsugu, Sato Kyoko, Oka Akira, Kamiguchi Hiroshi, Nagata Eiichiro, Sakura Hiroshi, Otsuka Kuniaki, Kobayashi Hiroyuki

Abstract excerpt

The objective of this study was to clarify the effects of disease on neurally mediated syncope (NMS) during an acute stress reaction. We analyzed the mechanism of the molecular interaction and the polymorphisms of the alpha-2 adrenoreceptor (α2B-AR) gene as the potential psychiatric cause of incentive stress. We focused on the following three genotypes of the repeat polymorphism site at Glu 301-303 in the α2B-AR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25860977
DOI: 10.1371/journal.pone.0120788
PMCID: PMC4393242

Genes

NMS

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