Article
Association study of single nucleotide polymorphisms on chromosome 19q13 with abdominal aortic aneurysm.
Angiology - 1 Apr 2010
Baas Annette F, Medic Jelena, van't Slot Ruben, de Vries Jean-Paul P M, van Sambeek Marc R H M, Geelkerken Bob H, Boll Bart P, Grobbee Diederick E, Wijmenga Cisca, Ruigrok Ynte M, Blankensteijn Jan D
Abstract excerpt
BACKGROUND: Abdominal aortic aneurysm (AAA) is a complex disorder in which environmental and genetic factors play a role in pathogenesis. Linkage to 2 adjacent loci on 19q13 in familiar AAA was previously demonstrated. We studied whether genetic variation within these regions predisposes to AAA. METHODS: Common genetic variants in the described regions on 19q13 were analyzed using tag single nucleotide...
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