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Article

Defective replication units of hepatitis B virus.

Journal of virology - 1 Apr 1990

Schranz P, Zentgraf H, Loncarević I F, Niepmann M, Schröder C H

Abstract excerpt

Templates for the synthesis of defective hepatitis B virus RNA pregenomes were constructed. Viral sequences in these constructs were replaced by the neomycin resistance gene. Deletions spanned up to 80% of the genome and did not include the cohesive end region. The size of the defective replication units was reduced up to half of the wild-type unit length. After cotransfection with replication competent wild-type...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2157068
DOI: 10.1128/JVI.64.4.1851-1854.1990
PMCID: PMC249328

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