Article
Amino acid changes in the L polymerase protein of vesicular stomatitis virus which confer aberrant polyadenylation and temperature-sensitive phenotypes.
Virology - 1 Apr 1993
Hunt D M, Hutchinson K L
Abstract excerpt
TsG16(I) is a temperature-sensitive mutant of vesicular stomatitis virus. In vitro, at the permissive temperature (31 degrees), it makes long poly(A) tracts, shows a larger increase in polyadenylation in the presence of S-adenosyl-homocysteine than its parental wt(Glasgow) virus, and makes an exc...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA, Viral
- Genes, Viral
- Molecular Sequence Data
- Mutation
- Phenotype
- Poly A
- Polymerase Chain Reaction
- RNA, Messenger
- RNA, Viral
- RNA-Dependent RNA Polymerase
- S-Adenosylhomocysteine
- Temperature
- Transcription, Genetic
- Vesicular stomatitis Indiana virus
- Viral Proteins
- Viral Structural Proteins